By Catherine Marcucci, Michael P. Hutchens et al. (eds.)
The incidence of deleterious or perhaps deadly drug-drug interactions (DDIs) within the perioperative interval is not any longer a theoretical hindrance yet a harrowing fact. A Case method of Perioperative Drug-Drug Interactions addresses the complicated realm of pharmacokinetic drug interactions in an easy-to-read quantity that capabilities as either a complete medical reference and a casebook. The publication provides a precis of the center strategies of drug interactions; an prepared, annotated presentation of the drug interactions so much suitable to the perioperative clinician; and nearly two hundred case situations that spotlight particular drug interactions. This booklet fills a true void within the scientific literature and is worthy to anesthesiologists and surgeons, in addition to trainees in either specialties; in depth care employees, together with physicians, physician’s assistants, and nurses; and nurse practitioners who employees preoperative review clinics.
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Extra info for A Case Approach to Perioperative Drug-Drug Interactions
Stacy L. Fairbanks MD 921 208 The Scary Side of Ginkgo Biloba Is No Match for an Anesthesia Superstar: Seizures . . . . . . . . . . . . . . . . . . . . Shreya Patel MD and Kirk Lalwani MD, FRCA, MCR 925 209 The Scary Side of Ginkgo Biloba Is No Match for an Anesthesia Superstar: Sugar . . . . . . . . . . . . . . . . . . . . . Shreya Patel MD and Kirk Lalwani MD, FRCA, MCR 929 210 The Scary Side of Ginkgo Biloba Is No Match for an Anesthesia Superstar: Subdural .
El-Baghdadi MD and Ibtesam A. Hilmi MB, CHB, FRCA 899 203 Enough to Make You Sick . . . . . . . . . . . . . . . . . . John Hache MD and Thomas M. Chalifoux MD 903 204 Determined and Desperate to Diet . . . . . . . . . . . . . . Lisa Chan MD and Kirk Lalwani MD, FRCA, MCR 909 XVIII Drug–Drug Interactions Involving Spices and Supplements 205 Introduction . . . . . . . . . . . . . . . . . . . . . . . Kirk Lalwani MD, FRCA, MCR 915 206 Caffeine Crash .
Continuous exposure to drugs may 2 Pharmacokinetic Interactions 13 cause receptor upregulation or downregulation and result in a change of overall receptor density. Tolerance may be to a single agent or to other drugs of a similar class or with a similar mechanism—a phenomenon often referred to as crosstolerance. Cross-tolerance between two different drugs may be complete (ie, similar in degree of tolerance) or incomplete (ie, tolerance is reduced in degree). An important point of consideration is that tolerance may also build up toward one effect of a drug and not another effect.